In a study of 37 patients with amyotrophic lateral sclerosis (ALS) (median age: 55 years; median symptom onset: 61 months), researchers found that vitamin D supplementation (2,000 international units daily) was safe over a period of 9 months and may have a beneficial effect on ALSFRS-R scores. Further studies are recommended to determine whether there is a benefit in vitamin D supplementation for all ALS patients.

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http://www.sciencedirect.com/science/article/pii/S0967586813001495