Vitamin D is referred to as a fat-soluble vitamin when in fact it is a pre-hormone, necessary for many body functions. It is stored in fatty tissue for longer periods of time.
Vitamin D is often considered the “sunshine” vitamin since production is stimulated through exposing the skin of your face, arms, back, or legs (without sunscreen) in the sun. It is said that 10-15 minutes of sunshine three times weekly is enough to produce the body’s requirement of Vitamin D.
Unfortunately, many people live in regions where days are predominantly cloudy, or have high pollution, or live in countries where full clothing is necessary, leaving the individuals with Vitamin D deficiencies.
Most of the positive effects of solar radiation are linked to ultraviolet-B (UVB) rays which are responsible of Vitamin D production in skin.
Some foods contain high amounts of Vitamin D, such as fatty fish (salmon & mackerel), grain cereals, oysters, caviar, fortified daily products, as well as soy products, but it is almost impossible to receive sufficient vitamin D from the diet. Be aware that some of these food sources may also be high in heavy metals; i.e. fish.
Vitamin D plays a vital role in the calcium & phosphorous absorption. A lack of Vitamin D in early age can cause bone and tissue malformation. Vitamin D-deficient children are known to suffer from rickets and osteoporosis later in life. Vitamin D also helps to keep the immune system strong and provides a protection from autoimmune diseases, hypertension, and infectious disease. Low vitamin D levels have been associated with an increased risk of developing cancer. Vitamin D deficiency has been linked to depression.
Kjaergaard M, Waterloo K, Wang K etc al. Effects of Vitamin D supplement on depression scores in people with low levels of serum 25-hydroxyvitamin D: nested case-control study and randomised trial. Br J Psychiatry. 2012 Jul 12.
A Vitamin D deficiency is a common occurrence, though often overlooked, which can result from:
Higher-than-normal levels of Vitamin D may be due to, a condition called Hypervitaminosis D, also known as Vitamin D toxicity. It is a rare but potentially serious condition that occurs when too much vitamin D is supplemented.
Vitamin D is easily measured in Serum, and the 25-hydroxy vitamin D test is considered the most accurate.
The test is simple and inexpensive.
Optimum Value in Serum is 40-60 µg/l.
Test material: 3ml Serum
(OMNS July 15, 2019) The results of a phase 2 randomized controlled trial (RCT) of high- vs. low-dose vitamin D3 supplementation for 139 patients with advanced colorectal cancer taking chemotherapy was recently reported in JAMA [Ng et al., 2019]. The high-dose vitamin D treatment was 8000 IU/d vitamin D3 for two weeks, then 4000 IU/d thereafter. The low-dose treatment group received 400 IU/d vitamin D3. The length of time before the disease worsened was 13 months in the high-dose treatment group and 11 months in the low-dose group. Further, high-dose vitamin D3 supplementation significantly reduced the risk of death by 36% (P = 0.02). In secondary analyses, the length of time before the disease worsened was significantly longer for patients in the treatment group who maintained a healthy weight, or had more metastatic sites.
The rate of diarrhea was 12% in the low-dose group, but only 1% in the high-dose group. This finding is consistent with the role of vitamin D in maintenance of gut mucosal barrier integrity.
(OMNS Feb 6 2019) The UVB-vitamin D-cancer hypothesis is nearly 40 years old [Garland, 1980]. There are 5293 publications with cancer and vitamin D or 25-hydroxyvitamin D [25(OH)D] in the title or abstract listed at pubmed.gov as of January 30, 2019. Nonetheless, this hypothesis has not been widely accepted; in fact, since the publication of the results for vitamin D supplementation for cancer in the VITamin D and OmegA-3 TriaL (VITAL) [Manson, 2019], support has been eroded further. As will be discussed here, the problem does not seem to be lack of evidence but, instead, the difference in how two cultures, the 'scientific' and the 'medical' communities, evaluate evidence.
Prof. Dr. med. Claus Schulte-Uebbing, Prof. Dr. med. Ingrid Gerhard and Doru Ioan Crăiut present proven vaginal high-dose vitamin D3 recipes for gynecological, urological and oncological practice.
New small studies have shown, that these recipes can be used for the treatment and prophylaxis of, among others, cervical dysplasia (CIN I), stress incontinence grade I, progesterone deficiency diseases (endometriosis, fibroids, adenomyosis) and e-deficiency colpitis.
Vitamin D deficient older individuals are more likely to struggle with everyday tasks such as dressing or climbing stairs, according to a recent study.
Clostridium difficile is the most common cause of nosocomial diarrhea, affecting up to 10% of hospitalized patients.
Researcher from the Johann Wolfgang Goethe University Hospital in Frankfurt, Germany has find out, that Vitamin D deficiency might be a key player in hepatitis B (HBV) replication.
Low levels of 25-hydroxyvitamin D (25(OH)D3) predicted high levels of the virus and vice versa.
Most of the positive effects of solar radiation are mediated via ultraviolet-B (UVB) induced production of vitamin D in skin. However, several other pathways may exist for the action of ultraviolet (UV) radiation on humans as focused on in this review. One is induction of cosmetic tanning (immediate pigment darkening, persistent pigment darkening and delayed tanning). UVB-induced, delayed tanning (increases melanin in skin after several days), acts as a sunscreen. Several human skin diseases, like psoriasis, vitiligo, atopic dermatitis and localized scleroderma, can be treated with solar radiation (heliotherapy) or artificial UV radiation (phototherapy). UV exposure can suppress the clinical symptoms of multiple sclerosis independently of vitamin D synthesis. Furthermore, UV generates nitric oxide (NO), which may reduce blood pressure and generally improve cardiovascular health. UVA-induced NO may also have antimicrobial effects and furthermore, act as a neurotransmitter. Finally, UV exposure may improve mood through the release of endorphins.
Researchers from a major medical center in New York have reported that 7 out of 10 U.S. children have low levels of vitamin D, placing them at higher risk for bone disorders, heart disease, and other health problems (Kumar 2009).
Obesity is associated with vitamin D deficiency, and both are areas of active public health concern. We explored the causality and direction of the relationship between body mass index (BMI) and 25-hydroxyvitamin D [25(OH)D] using genetic markers as instrumental variables (IVs) in bi-directional Mendelian randomization (MR) analysis.
In recent years, healthy people have been bombarded by stories in the media and on health websites warning about the dangers of too-low vitamin D levels, and urging high doses of supplements to protect against everything from hypertension to hardening of the arteries to diabetes.
Mushrooms are the only vegetarian food that can make Vitamin D.