17. July 2007
A University of Toronto study is the first in North America to draw a link between Parkinson's and manganese air pollution, and suggests industry-generated pollutants poses a greater health risk than traffic-generated manganese.
Murray Finkelstein, assistant professor in the department of family and community medicine, worked with Berkeley professor Michael Jerrett to compare the incidence of diagnosis and treatment of Parkinson's with markers of exposure to vehicle exhaust and industrial emissions in the cities of Toronto and Hamilton. The study, which examined a cohort of 110,000 subjects over three years, appeared in Environmental Research 2007.
“The results suggest that the manganese threat posed by traffic-generated pollution may be relatively small, but that exposure to ambient manganese in the air from sources like steel foundries does advance the age of diagnosis of Parkinson's disease,” said Finkelstein. “This study supports the theory that exposure to manganese adds to the natural loss of neurons attributable to the aging process.”
Einer Studie der University of Pennsylvania Health System zufolge, gibt es einen Zusammenhang von Parkinson Erkrankung und Mangan-Vergiftung
Manganismus oder Manganvergiftung ist in Bergbauberufen und der Schweiß- und Stahlherstellung weit verbreitet. Diese wird durch die Einwirkung von hohen Mengen des Metalls Mangan verursacht, die das zentrale Nervensystem angreifen, das macht sich in mortorischen- und Demenzsymptomen bemerkbar, die der Parkinson-Krankheit ähneln.
Lesen Sie mehr im englischen Orginal Artikel:
14 patients with Parkinson Disease (PD) and 14 control patients were randomly selected and examined for cutaneous eruptions and blood mercury levels. Of the 14 PD patients, 13 had Grover's Disease (which results in red, bumpy skin eruptions) and detectable blood mercury levels. None of the patients in the control group had skin eruptions and only 2 had detectable blood mercury levels.
Dantzig PI. A new cutaneous sign of mercury poisoning? J Am Acad Dermatol. 2003;49:1109-1111
Bjørklund G. Parkinson’s Disease and Mercury. Journal of Orthomolekulare Medicine 1995; 10: 147-148.